A gene mutation linked to schizophrenia may cause the brain to cling to outdated beliefs by disrupting a key decision-making circuit. Scientists were able to reverse this effect in mice, suggesting a promising new treatment target.
  • deafboy@lemmy.world
    0·
    26 days ago

    Only a small percentage of schizophrenia patients carry mutations in grin2a. However, the researchers believe this circuit may represent a shared pathway that contributes to cognitive impairment across different forms of the disorder.

    And yet, the title still mentions schizophrenia. I guess the author is stuck with the incorrect prediction…

  • acockworkorange@mander.xyz
    0·
    26 days ago

    Scientists at MIT may have found a key reason. A newly identified gene mutation appears to disrupt a brain circuit that helps us update our understanding of the world. When this system fails, the brain may cling to old ideas even when reality changes.

    Thank you, nameless scientists.