Nearly every cartridge-based system up until the 3DS n the cartridge. But many older cartridge games from that era (SNES, GBC, sometimes GBA) used volatike SRAM that needs to be constantly powered with an internal battery. When the battery dies, the save is wiped and it can no longer hold a save, though you can always open the cart up and replace the battery.
Nearly every cartridge-based system up until the 3DS n the cartridge. But many older cartridge games from that era (SNES, GBC, sometimes GBA) used volatike SRAM that needs to be constantly powered with an internal battery. When the battery dies, the save is wiped and it can no longer hold a save, though you can always open the cart up and replace the battery.