That’s great but I’ve been seeing articles like this for decades so I’ll believe it when there’s an actual working product you can actually get
They’re progressing slowly, but it’s obvious that they don’t want a bad launch so they’re all waiting until they have something that works and is safe enough and safety only comes from having people take it then see if it works after being reversed or ended years later.
Right? Im scheduled for a vasectomy in a month, this ain’t stopping me.
One of the best moves I made.
After my partner and I had agreed no more kids…it was down to the doc to get the chop. Very easy, keyhole surgery; I feeling 90% by the next day, 100% the following day. 2.5 days of discomfort for years of stress free times…worth it!
You can self heal after a vasectomy. It’s rare but happens. Especially in the first few years following the procedure.
But easy enough to go to your dr every few years and get tested.
Never regretted it myself, but technically quite a good chance of reversibility (85+%) and 95+% chance of viable artificial insemination if things change.
Also minimal, short lived discomfort.
It’s considered permanent though. Shouldn’t go ahead under view it can be reversed. Saying that, the piece of mind it brings is wonderful.
Also, compare those to the near certain side effects of female contraception, which is just taken as the natural state of affairs.
Valid, those are pretty good odds though, mind you I looked it up decades ago and the reversal was a pretty involved piece of expensive microsurgery.
Best $50 I’ve ever spent. Quick procedure, quick recovery with an excuse to not do anything for a couple days.
50$??? Where do you live? Can I live there?
Midwest here. Just had the procedure about two weeks ago (recovery slightly slower than the commenter above, but not by much). They said something like $500 without insurance which honestly wasn’t even that bad. After insurance it was $110. One consultation of “you sure big dawg?” Then the procedure about 4 weeks later, which took maybe 20-30 minutes and I was just chatting away with some Valium in my system. Very easy.
It’s free and covered by universal healthcare here in Canada. You just have to ask for one.
Midwest US, but it’s really down to the insurance policy. This particular procedure was 100% covered other than copay. Copay was usually $50, but for specialties it was $75. If you have insurance, definitely check your policy. A lot of times vasectomy is explicitly called out.
You can so just be brown and walk in front of ICE. They have a history of forced sterilizing
Jesus, you’re not making that up. I think that may ruin my night.
That shit is copay. Can’t even get a cat neutered for $50.
Scientists at Cornell University
may be
closing in
Testosterone is a fairly effective male contraceptive agent, but most people can’t get over the side effect of ball shrinkage.
Hmm. And what “debuffs” (for a lack of a better term, lol) can a male experience from this side effect?
deleted by creator
Makes me wonder how many side-effects women birth-control had when it was approved for the public.
🙂😐🫣☠️
deleted by creator
Not having sex is also apparently worse than the side effects.
deleted by creator
Still a choice.
deleted by creator
Well that’s an easy way to avoid reflecting on your own beleifs.
The shit women deal with, I don’t see how anyone could look at them and say they’re weak. It’s beyond me.
Because they’re clearly weak in ways that are highly visible.
deleted by creator
Being strong one way doesn’t make women strong in all ways, either. So in some way, that are very visible, women are weak. That’s the answer to the question asked, you don’t need to like it.
What? Are we going with how evolution has made us? Sure. There’s a difference between us, but that doesn’t make em weak. I believe in evolution and nature. With that, I can acknowledge the difference. But weak? Bullshit. The average woman might have different strengths than the average man, but that doesn’t mean shit. We defy nature. Every day, we defy nature. Plus, with that, you could say there’s things they are better at than men.
My partner is way better at managing things for us. So, should I never lead anything or anyone? I mean, the best managers I’ve had were women. My dad was shit at keeping bills paid, but my ma did it all while cleaning a house. So, should all men be treated like babies who can’t handle money or be responsible for themselves?
I don’t know about you, bud, but I prefer to be my own human and handle my own shit. My partner is my equal, just like all women are my equal. Cause I don’t know their strengths and weaknesses. They’re a human. They defy nature in whatever way they want, just like me.
Clearly this topic makes you a little defensive and that’s a whole lot of extrapolation and assumption I’m not interesting in wading through.
Sure, buddy. Nothing I said was complex. But you do, you bud.
deleted by creator
Oh dude I know it. In the beginning of my partner and mine’s relationship, she was constantly throwing up in the middle of the night. This went on for like 3-4 yrs. The doctors gave us a bunch of bullshit about it. Told her basically it was her fault. Ended up being her birth control.
She had an iud at one time that gave her cysts in her ovaries. I have seen this woman be in so much pain and stuff it down to keep going through the day.
I’ll fucking fight you (not you) if you say women are weak to my face.
deleted by creator
iirc, the first daily pills had the dosage of our current morning after pill. From what I understand, the morning after pill makes you feel like complete shit and they were taking it everyday.
deleted by creator
Yes that’s what I meant. It doesn’t make sense because I meant to reply to the comment you replied to and not yours. My mistake, woops.
Now I’m curious if irreversible methods are considered “birth control.” It seems redundant to write “reversible birth control,” but maybe I’ve been using too narrow a definition. I consider IUDs to be birth control, but not vasectomies. The distinction is the level of effort required to reverse.
If completely irreversible, is that not considered sterilization?
deleted by creator
I had a vasectomy because I don’t want any more children, I think that counts as birth control. Anything that prevents conception is contraceptive in nature.
So, sterilization is a subset of birth control methods.
deleted by creator
deleted by creator
To achieve this, scientists used JQ1, a small molecule inhibitor originally developed to study cancer and inflammatory diseases. While JQ1 is not suitable as a treatment due to neurological side effects, it is known to interfere with a stage of meiosis called prophase 1.
Bruh the cancer lab (prostate cancer out of all things) I worked in as an undergrad was studying JQ1. Couldn’t believe I’d ever hear this drug name again. Really hope this can go somewhere, reversible contraceptive sounds exciting
You still in the field or did you go another way?
I’m back in cancer research for my current job again. But not in prostate… and more importantly, I’m on the computational side of things instead of experimental now
Also as to the topic… there were a few people in my undergrad lab who were actively studying JQ1 (back in 2017-18), but I’ve never heard much about the drug after I left. Thanks to you I finally found out why I never heard about it again (neurological side effects) so
its just a feeling I can relate to. I moved from blood diagnostics to it looooooonnnng ago.
Yes, I know some of these words and concur.
So the substance isn’t a possible treatment for cancer because of neurological side effects… and their next step is “let’s sell it to guys who aren’t able to use condoms”?
I think the idea is that this particular drug isn’t suitable as birth control, but having identified that this mechanism/biological pathway can work for birth control, they can look for a less toxic compound to achieve the same effect.
If I read it correctly it’s double win for guys who have cancer and don’t want to reproduce.
sounds that way to me. I think the thing like always is the title. its something they noticed and now a track to find something that does a similar type of mechanism without the bad side effects.
While JQ1 is not suitable as a treatment due to neurological side effects
That doesn’t sound very safe.
Should have just used bleach if they don’t care about it actually being a viable treatment. Or, for that matter, we’ve already invented spermicidal foam…
Excellent. Now all those “but I can’t get a vasectomy” guys have another option. Beyond time to put the onus for not reproducing on the male side of the equation.
Can’t get a vasectomy if you plan having kids.
But actual issue is no, we do not have another option, because this study has been done on mice, so even if it would actually happen it would take easily 10 years before it would go to market.
What’s worse is that it won’t happen. Google RISUG, Smart RISUG, Vasalgel and Plan A.
These are simple polymers that are injected into the vas deferens of a man and stay there for years up to decades, making the man sterile. It’s easily reversible, has no side effects and just disables fertility. And it’s been blocked by pharma companies since the 70s, because it would cost them massive amounts of money if women wouldn’t need to pay for expensive and short-lasting contraception methods.
The situation that only women have access to decent methods of contraception sucks, and the most infuriating part is that it doesn’t have to be, but because it would cost some rich assholes money, they purposely keep the situation as is.
Believe me, most men would much prefer to have access to good methods of contraception, but we are essentially stuck at the same level since the 1920s.
deleted by creator
Yeah, I’d say having a study participant trying to commit suicide because of the birth control is kinda severe.
But also look at who cancelled the study. Was it the participants? Was it the potential customers? Or was it a company that was afraid of lawsuits?
I don’t like you trying to blame “the men” because some suits pulled the plug because they feared losing money.
The thing with the vasalgel/RISUG thing is that there aren’t any reported side effects and it still was cancelled.
If you look at actual research, there’s actually quite a demand for novel male contraception methods:
The proportion of male participants in clinical trials reporting willingness to use a male contraceptive ranged from 34% to 82% and the proportion from surveys about hypothetical methods ranged from 14% to 83% [2]. Specific to the United States (US), a population survey conducted in 2002 of 1500 men reported willingness among 49.3% of respondents [6]; two decades later, an online survey of 2066 men from the US and Canada reported willingness among 75% of respondents
https://www.sciencedirect.com/science/article/pii/S001078242400101X
deleted by creator
According to the head of urology for a very large research hospital here, they’ve never been reversible (after a few months, max) and he was very clear about that before he started with the laser.
deleted by creator
The doctor that did mine; made sure that I knew that it whilst it was theoretically reversible; it is a major surgery vs a minor one to get it done, and the success rate is very low ~20%. So best consider a vasectomy as permanent and irreversible.
Because people are fucking stupid, and even stupider people prey on them en masse. Simple as.
deleted by creator
Motivation? To be fair, I have no idea beyond conjecture, though the effects certainly play nice with their other methods of misinformation and target results: distraction, uncertainty, decay of trust, perforation of hope, community attrition, isolation, division, et al.
If no one’s trustworthy, how can a rebellion even spark much less foment effectively? If the primary source of this oppression is obfuscated to look like scores of minor psychopaths instead, how will any resistance unify itself?
Keeping us dumb, testy, and drained makes bawbags of us all. 🤌🏼
Why does the egg look like that??
They’ve had something similar available for years. It’s a small plastic square about the size of a lego brick. You put it in your shoe and it makes you limp
There was this gel that got injected into the tube connecting the balls to the urethra(vas deferens?). It would destroy the sperms as it went through and you where basically sterile. To reverse they injected you again with something and it would become a liquid and you ended up busting it out in a few ejaculations. It’s been stuck in early human trials for a decade.
deleted by creator
I’ve giving up and just saving for a vasectomy now. Whatever it costs is still cheaper than a kid
deleted by creator
100% this.
I know of a few people that this happened to…make sure you are testing 0% sperm count before going “hats off”
Even if it’s zero percent at the test, does that mean all future ejaculations will be 0%?
Oh absolutely. These kids gonna eat me out of house and home. I ain’t trusting it until after I’ve been given the all clear and still pulling out just in case
Jesus, I read about that technique in a science magazine in the 90s.
I thought this was being tested a couple of years ago?
…in mice, after massive, cancer-causing doses, probably.
I’m tired of hearing about this shit. Put it to market or stop talking about it.
Yeah just push it out to public. Just like they did with women’s contraceptives.
Last I heard there were some of these contraceptives moving into clinical trials, the ones with gel in the vas deferens,
Anyway it is irrelevant for regular people, because it isn’t available and probably won’t be within 5 to 10 years if lucky. Maybe it would be relevant if it had a chance of being available in 1 to 2 years , even then who knows how expensive it would be or how long it would take to be accessible, as in a lot of doctors doing it.
Vasagel, based on an Indian product called RISUG
Noone funds it because it’s too cheap? No real profit potential?
Essentially – it’s a gel that’s injected into the vas def which doesn’t actually block the flow totally (which sometimes causes side effects like granuloma in vasectomy), but rather it disrupts sperm cell membranes, but allowing the remains to pass through.
It is reversed simply by flushing it out with saline.
Last time I donated to the project it was at the live rabbit trials stage with Parsemuns Foundation?
(OH WAIT IT HAS BEEN USED IN HUMANS IN THE USA (see wired link below)
RISUG was used in humans for like 20 years with good results I believe.
Really don’t understand why this one hasn’t gained traction.
https://www.planaformen.com/vasalgel
https://en.wikipedia.org/wiki/Reversible_inhibition_of_sperm_under_guidance
https://www.wired.com/story/male-contraceptive-contraline-vasalgel-hydrogel/
(Ohh right the rabbit study was for reversibility)
this is way less reversible than they claim
This kind of news is an annual event at this point.
Easier to target one egg cell than millions of sperm germ cells.
Sure. But the demand is here on both sides, not just one.
Male contraceptives allow men to have reproductive agency beyond condoms and vasectomy, and they can be used in couples where women prefer not to use non-barrier contraception for health reasons or personal reservations.
My situation right here. Condoms suck, vasectomy is too much, and birth control isn’t on the table. Please give me a pill already.
I have a different solution, its called being a transbian :3
How so? Unless you remove testicles, or your partner is also a trans person, you’re still 100% able to have offspring together
I was being more silly than serious :3
Hehe alright!
