They’ve had something similar available for years. It’s a small plastic square about the size of a lego brick. You put it in your shoe and it makes you limp
Easier to target one egg cell than millions of sperm germ cells.
Sure. But the demand is here on both sides, not just one.
Male contraceptives allow men to have reproductive agency beyond condoms and vasectomy, and they can be used in couples where women prefer not to use non-barrier contraception for health reasons or personal reservations.
My situation right here. Condoms suck, vasectomy is too much, and birth control isn’t on the table. Please give me a pill already.
I have a different solution, its called being a transbian :3
How so? Unless you remove testicles, or your partner is also a trans person, you’re still 100% able to have offspring together
I was being more silly than serious :3
Hehe alright!
Kinda hard to make male contraceptives. Women are naturally infertile for most of the time not spent actively ovulating. They are permanently infertile during pregnancy, real or synthetic. But men? We’re always churning out swimmers. When that process stops, something has gone very wrong.
So, artificially induce a naturally occurring phenomenon vs artificially terminate a constant mechanism.
It is more difficult, but still worth working towards it.
Well not with that attitude!
We need this just because Republicans would never tell a straight white man what to do with his body…
And any birth control is better than none, for the periods we can’t have all methods.
Are the republicans against the draft and the forced labour prison system? Quite a few straight white men there
Cool. More options for reproductive agency are always welcome.
Isn’t that called taking HRT?
Not if you know what acronyms stand for or words mean…
a safe, reversible, nonhormonal method that completely halts sperm production. I
Summary:
Scientists at Cornell University may be closing in on the long-sought “holy grail” of male contraception: a safe, reversible, nonhormonal method that completely halts sperm production. In a breakthrough mouse study, researchers used a compound called JQ1 to temporarily shut down meiosis—the critical process that produces sperm—without causing lasting harm. After treatment stopped, sperm production bounced back, fertility returned, and the animals produced healthy offspring.
ah so it’s one of those articles whose title is missing “in mice”
And I question how viable it is given this:
To achieve this, scientists used JQ1, a small molecule inhibitor originally developed to study cancer and inflammatory diseases. While JQ1 is not suitable as a treatment due to neurological side effects, it is known to interfere with a stage of meiosis called prophase 1. This allowed researchers to demonstrate, for the first time, that targeting meiosis can safely and reversibly shut down sperm production.
It sounds like calling the treatment “safe” might be a bit of a stretch.
I think they meant “safe” with regard to reproductive ability. It sounds like they’re happy with targeting meiosis, not with using JQ1 specifically.
Aren’t pretty much all of these medical discoveries from mice?
It’s an early step. Good chance it doesn’t work well in humans, and many side effects can’t be discovered until human trials either.
The “in mice” part is actually really exciting to me because male pet mice have to be kept solitary to prevent pregnancies and aggression with other males, but they still have social needs. It would be amazing if they could be kept with females full-time with no pregnancy risk.
Would also be nice to keep mixed-mischiefs of rats since their personalities and behaviors are somewhat sexually divergent. You could have a couple busy girls and a couple cuddly boys without having to take turns free roaming.
They have no real idea what harm it may cause. Sterilizing people with an unknown method and promising it’s ‘reversible’ is capitalist propaganda.
While JQ1 is not suitable as a treatment due to neurological side effects, it is known to interfere with a stage of meiosis called prophase 1. This allowed researchers to demonstrate, for the first time, that targeting meiosis can safely and reversibly shut down sperm production.
If developed for human use, this type of male contraceptive could be delivered as an injection given every three months or possibly as a patch to maintain effectiveness, Cohen said.
Awesome! Most other male birth control methods have been left by the wayside because of the adverse side effects. This sounds promising.
Makes me wonder how many side-effects women birth-control had when it was approved for the public.
🙂😐🫣☠️
Oh so many side effects. Issue is that pregnancy is worse than most of those side effects and that disproportionally affects women.
iirc, the first daily pills had the dosage of our current morning after pill. From what I understand, the morning after pill makes you feel like complete shit and they were taking it everyday.
What birth control pill are you talking about? This is too vague and I’ve never heard of this.
Edit: Oh are you talking about the very first birth control pills that were introduced? That would make sense. Modern birth control pills have a lot of side effects, too, so I’m not sure what the point of your comment was.
Yes that’s what I meant. It doesn’t make sense because I meant to reply to the comment you replied to and not yours. My mistake, woops.
The shit women deal with, I don’t see how anyone could look at them and say they’re weak. It’s beyond me.
Because they’re clearly weak in ways that are highly visible.
As if there’s only one way to be strong lol
Being strong one way doesn’t make women strong in all ways, either. So in some way, that are very visible, women are weak. That’s the answer to the question asked, you don’t need to like it.
What? Are we going with how evolution has made us? Sure. There’s a difference between us, but that doesn’t make em weak. I believe in evolution and nature. With that, I can acknowledge the difference. But weak? Bullshit. The average woman might have different strengths than the average man, but that doesn’t mean shit. We defy nature. Every day, we defy nature. Plus, with that, you could say there’s things they are better at than men.
My partner is way better at managing things for us. So, should I never lead anything or anyone? I mean, the best managers I’ve had were women. My dad was shit at keeping bills paid, but my ma did it all while cleaning a house. So, should all men be treated like babies who can’t handle money or be responsible for themselves?
I don’t know about you, bud, but I prefer to be my own human and handle my own shit. My partner is my equal, just like all women are my equal. Cause I don’t know their strengths and weaknesses. They’re a human. They defy nature in whatever way they want, just like me.
Clearly this topic makes you a little defensive and that’s a whole lot of extrapolation and assumption I’m not interesting in wading through.
Sure, buddy. Nothing I said was complex. But you do, you bud.
It’s even better (worse) - women’s self-reported pain levels and symptoms are often dismissed and underestimated by doctors and researchers.
So even when reporting on the side-effects on birth control, women are not taken seriously.
Oh dude I know it. In the beginning of my partner and mine’s relationship, she was constantly throwing up in the middle of the night. This went on for like 3-4 yrs. The doctors gave us a bunch of bullshit about it. Told her basically it was her fault. Ended up being her birth control.
She had an iud at one time that gave her cysts in her ovaries. I have seen this woman be in so much pain and stuff it down to keep going through the day.
I’ll fucking fight you (not you) if you say women are weak to my face.
I’ll fucking fight you (not you) if you say women are weak to my face.
Thanks dude/dudette. It’s refreshing to see this energy here and it’s really awesome.
Not having sex is also apparently worse than the side effects.
Yeah that’s like totally a valid option for the billions of couples out there.
Just stop having sex, you silly women! Duh!
Still a choice.
It’s not always a choice. But I gather you don’t really give a fuck about women anyway.
Have the day you deserve!
Well that’s an easy way to avoid reflecting on your own beleifs.
Now I’m curious if irreversible methods are considered “birth control.” It seems redundant to write “reversible birth control,” but maybe I’ve been using too narrow a definition. I consider IUDs to be birth control, but not vasectomies. The distinction is the level of effort required to reverse.
If completely irreversible, is that not considered sterilization?
Sterilization is a type of birth control. It’s just a permanent type.
I would consider getting tubes tied a form of birth control.
I had a vasectomy because I don’t want any more children, I think that counts as birth control. Anything that prevents conception is contraceptive in nature.
So, sterilization is a subset of birth control methods.
Yes, what else is sterilization for if not for birth control?
Yeah isn’t one of the only goals for a vasectomy birth control? I’d be curious to know if there are other reasons to get a vasectomy besides that.
Excellent. Now all those “but I can’t get a vasectomy” guys have another option. Beyond time to put the onus for not reproducing on the male side of the equation.
Tbf vasectomies should not be seen as reversible, so it’s really not a good form of birth control for those that still want kids in the future.
According to the head of urology for a very large research hospital here, they’ve never been reversible (after a few months, max) and he was very clear about that before he started with the laser.
Yep! Which is why is still puzzling to see this “vasectomies are reversible” sentiment still being pushed.
The doctor that did mine; made sure that I knew that it whilst it was theoretically reversible; it is a major surgery vs a minor one to get it done, and the success rate is very low ~20%. So best consider a vasectomy as permanent and irreversible.
Because people are fucking stupid, and even stupider people prey on them en masse. Simple as.
What’s the motivation for preying on people to get them to believe vasectomies are reversible?
Motivation? To be fair, I have no idea beyond conjecture, though the effects certainly play nice with their other methods of misinformation and target results: distraction, uncertainty, decay of trust, perforation of hope, community attrition, isolation, division, et al.
If no one’s trustworthy, how can a rebellion even spark much less foment effectively? If the primary source of this oppression is obfuscated to look like scores of minor psychopaths instead, how will any resistance unify itself?
Keeping us dumb, testy, and drained makes bawbags of us all. 🤌🏼
Can’t get a vasectomy if you plan having kids.
But actual issue is no, we do not have another option, because this study has been done on mice, so even if it would actually happen it would take easily 10 years before it would go to market.
What’s worse is that it won’t happen. Google RISUG, Smart RISUG, Vasalgel and Plan A.
These are simple polymers that are injected into the vas deferens of a man and stay there for years up to decades, making the man sterile. It’s easily reversible, has no side effects and just disables fertility. And it’s been blocked by pharma companies since the 70s, because it would cost them massive amounts of money if women wouldn’t need to pay for expensive and short-lasting contraception methods.
The situation that only women have access to decent methods of contraception sucks, and the most infuriating part is that it doesn’t have to be, but because it would cost some rich assholes money, they purposely keep the situation as is.
Believe me, most men would much prefer to have access to good methods of contraception, but we are essentially stuck at the same level since the 1920s.
The situation that only women have access to decent methods of contraception sucks, and the most infuriating part is that it doesn’t have to be, but because it would cost some rich assholes money, they purposely keep the situation as is.
There is that angle as well as the fact that most men would not use male birth control if there are side effects.
Women have more motivation to be on birth control regardless of the side effects because pregnancy is a worse outcome than those side effects.
For years, people have tried to create birth control for men. The World Health Organization commissioned what sounded like a promising trial, a two-hormone injection designed to lower sperm count. Initial results looked like it would be 96 percent effective in preventing pregnancy in the participants’ partners. But the Stage II trial was stopped after an independent review panel found that the drug had too many side effects. The results were published last week in The Journal of Clinical Endocrinology and Metabolism.
Yeah, I’d say having a study participant trying to commit suicide because of the birth control is kinda severe.
But also look at who cancelled the study. Was it the participants? Was it the potential customers? Or was it a company that was afraid of lawsuits?
I don’t like you trying to blame “the men” because some suits pulled the plug because they feared losing money.
The thing with the vasalgel/RISUG thing is that there aren’t any reported side effects and it still was cancelled.
If you look at actual research, there’s actually quite a demand for novel male contraception methods:
The proportion of male participants in clinical trials reporting willingness to use a male contraceptive ranged from 34% to 82% and the proportion from surveys about hypothetical methods ranged from 14% to 83% [2]. Specific to the United States (US), a population survey conducted in 2002 of 1500 men reported willingness among 49.3% of respondents [6]; two decades later, an online survey of 2066 men from the US and Canada reported willingness among 75% of respondents
https://www.sciencedirect.com/science/article/pii/S001078242400101X
…in mice, after massive, cancer-causing doses, probably.
I’m tired of hearing about this shit. Put it to market or stop talking about it.
Yeah just push it out to public. Just like they did with women’s contraceptives.
There was this gel that got injected into the tube connecting the balls to the urethra(vas deferens?). It would destroy the sperms as it went through and you where basically sterile. To reverse they injected you again with something and it would become a liquid and you ended up busting it out in a few ejaculations. It’s been stuck in early human trials for a decade.
This is the one my husband has been keeping a close eye on for years. Shame it hasn’t moved much recently.
I’ve giving up and just saving for a vasectomy now. Whatever it costs is still cheaper than a kid
Make sure you do your follow up exams! Don’t want a kid-shaped surprise after going through the hoops to get a vasectomy lol
100% this.
I know of a few people that this happened to…make sure you are testing 0% sperm count before going “hats off”
Oh absolutely. These kids gonna eat me out of house and home. I ain’t trusting it until after I’ve been given the all clear and still pulling out just in case
Even if it’s zero percent at the test, does that mean all future ejaculations will be 0%?
Jesus, I read about that technique in a science magazine in the 90s.
That’s great but I’ve been seeing articles like this for decades so I’ll believe it when there’s an actual working product you can actually get
Right? Im scheduled for a vasectomy in a month, this ain’t stopping me.
Never regretted it myself, but technically quite a good chance of reversibility (85+%) and 95+% chance of viable artificial insemination if things change.
Also minimal, short lived discomfort.
It’s considered permanent though. Shouldn’t go ahead under view it can be reversed. Saying that, the piece of mind it brings is wonderful.
Also, compare those to the near certain side effects of female contraception, which is just taken as the natural state of affairs.
Valid, those are pretty good odds though, mind you I looked it up decades ago and the reversal was a pretty involved piece of expensive microsurgery.
Best $50 I’ve ever spent. Quick procedure, quick recovery with an excuse to not do anything for a couple days.
50$??? Where do you live? Can I live there?
Midwest here. Just had the procedure about two weeks ago (recovery slightly slower than the commenter above, but not by much). They said something like $500 without insurance which honestly wasn’t even that bad. After insurance it was $110. One consultation of “you sure big dawg?” Then the procedure about 4 weeks later, which took maybe 20-30 minutes and I was just chatting away with some Valium in my system. Very easy.
That shit is copay. Can’t even get a cat neutered for $50.
It’s free and covered by universal healthcare here in Canada. You just have to ask for one.
You can so just be brown and walk in front of ICE. They have a history of forced sterilizing
Jesus, you’re not making that up. I think that may ruin my night.
Midwest US, but it’s really down to the insurance policy. This particular procedure was 100% covered other than copay. Copay was usually $50, but for specialties it was $75. If you have insurance, definitely check your policy. A lot of times vasectomy is explicitly called out.
One of the best moves I made.
After my partner and I had agreed no more kids…it was down to the doc to get the chop. Very easy, keyhole surgery; I feeling 90% by the next day, 100% the following day. 2.5 days of discomfort for years of stress free times…worth it!
You can self heal after a vasectomy. It’s rare but happens. Especially in the first few years following the procedure.
But easy enough to go to your dr every few years and get tested.
Scientists at Cornell University
may be
closing in
They’re progressing slowly, but it’s obvious that they don’t want a bad launch so they’re all waiting until they have something that works and is safe enough and safety only comes from having people take it then see if it works after being reversed or ended years later.
Testosterone is a fairly effective male contraceptive agent, but most people can’t get over the side effect of ball shrinkage.
Hmm. And what “debuffs” (for a lack of a better term, lol) can a male experience from this side effect?
